Changes are necessary as well as preferable when Manchester United face Southampton this weekend.
Luke Shaw is sidelined with injury while the MEN report Anthony Martial is a doubt.
Working on the basis Martial may not be fit to start, we are predicting three changes to the team which lost to Crystal Palace last Saturday.

The third change would see Jesse Lingard drop out to make way for Andreas Pereira.
Ashley Young is most likely to start at left-back, with Mason Greenwood replacing Martial.
Here is a look at how the team could line up…

Bringing in Mason Greenwood gives United the additional firepower lost by Martial.
He showed in pre-season he can play on the right, and this would enable Dan James to play in his more natural position on the left. It was from here where the Welshman scored against Palace.
Big decisions
Pereira is one of the more obvious choice to replace Jesse Lingard, who is woefully out of form.
We are not convinced Ole Gunnar Solskjaer won’t pick Lingard, as he might feel his pressing could be useful away from home.
Yet Lingard has offered so little on the ball this season, that picking him seems more detrimental than beneficial. Pereira has been unlucky not to have been given the chance to build on his opening weekend display.

Ashley Young is most probable to start at left-back, but we would love to see teenager Brandon Williams get a place on the bench.
Tahith Chong shone for the under-23s last week and he will feel he too deserves a step up, and there are calls for Angel Gomes to also to get a chance.
Solskjaer’s selection of substitutes will be almost as interesting as the team he picks.
- Confirmed Manchester United starting line-up against Nottingham Forest
- Jadon Sancho pictured arriving at Old Trafford for Manchester United semi-final second leg
- How many transfer windows Phil Jones has now survived as a Manchester United player
- Rio Ferdinand responds to Paul Merson over Marcel Sabitzer criticism
- Can Marcel Sabitzer play in the Europa League? Eligibility and suspension explained