Manchester United sign off before the international break with an FA Cup quarter-final clash with Fulham at Old Trafford.
United got back to winning ways on Thursday night against Real Betis, with Marcus Rashford earning a 1-0 win in Spain.
This match is the first of four domestic games Casemiro will miss with the suspension he picked up for a second red card of the season against Southampton.
Predicted Manchester United XI to face Fulham in the FA Cup
In goal, we would expect David de Gea to continue, with Lisandro Martinez and Aaron Wan-Bissaka keeping their places in front of him in the back four.
Luke Shaw and Raphael Varane were rested in midweek but we would expect them both to come into the team for a game where a win sets up a semi-final clash at Wembley.
Erik ten Hag may not have too many choices with which to replace Casemiro, given Scott McTominay is now a doubt for the game.
Christian Eriksen and Donny van de Beek are still out, so there may not be much choice but to give Marcel Sabitzer his first start after injury.
Fred and Bruno Fernandes would expect to continue in midfield, with Marcus Rashford another certain starter on the left hand side of the attack.
Wout Weghorst has started every game since his arrival and given Anthony Martial has already been ruled out, he looks set to get the nod again here.
Facundo Pellistri started in Betis, but Ten Hag tends to manage his young players very carefully, and with Antony doubtful and Alejandro Garnacho out, Jadon Sancho would be the obvious choice to replace him.
OUT: Harry Maguire, Tyrell Malacia, Casemiro, Facundo Pellistri.
IN: Raphael Varane, Luke Shaw, Marcel Sabitzer, Jadon Sancho.